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Article

MicroRNAs Regulate the Pathogenesis of CVB3-Induced Viral Myocarditis

23 Nov 2012

Abstract excerpt

AIMS: To evaluate the role of microRNAs (miRNAs) in the pathogenesis of Coxsackievirus B3 (CVB3)-induced viral myocarditis. METHODS: We detected miRNA expression profiling by microarray utilizing a mouse model on day 4 after CVB3 infection. Then we validated differentially expressed miRNAs using real-time polymerase chain reaction (PCR). We predicted target genes using miRNA target prediction databases and...

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PMID: 23183417
DOI: 10.1159/000343750

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