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Article

An autophagy-independent role for LC3 in equine arteritis virus replication

26 Nov 2012

Abstract excerpt

Equine arteritis virus (EAV) is an enveloped, positive-strand RNA virus. Genome replication of EAV has been associated with modified intracellular membranes that are shaped into double-membrane vesicles (DMVs). We showed by immuno-electron microscopy that the DMVs induced in EAV-infected cells contain double-strand (ds)RNA molecules, presumed RNA replication intermediates, and are decorated with the autophagy...

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PMID: 23182945
DOI: 10.4161/auto.22743

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