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Biogenesis and architecture of arterivirus replication organelles

10 Apr 2016

Abstract excerpt

All eukaryotic positive-stranded RNA (+RNA) viruses appropriate host cell membranes and transform them into replication organelles, specialized micro-environments that are thought to support viral RNA synthesis. Arteriviruses (order Nidovirales) belong to the subset of +RNA viruses that induce double-membrane vesicles (DMVs), similar to the structures induced by e.g. coronaviruses, picornaviruses and hepatitis C...

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PMID: 27071852
DOI: 10.1016/j.virusres.2016.04.001

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