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Pseudorabies virus gM protein and herpesvirus homologs block selective autophagy to enhance viral replication

3 Jun 2025

Abstract excerpt

Macroautophagy/autophagy is a biological process that sequesters and degrades cytoplasmic material, damaged organelles, and infectious pathogens in eukaryotic cells via lysosomes. Autophagy is involved in different phases of the viral life cycle and regulates viral replication. Here, we demonstrated that pseudorabies virus (PRV) infection induced incomplete autophagy, and blocking the autophagosome-lysosome...

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PMID: 40462306
DOI: 10.1080/15548627.2025.2511584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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