Article
Spermatogenic defects in F2 mice between normal mouse strains C3H and C57BL/6 without mutation.
Congenital anomalies - 1 Dec 2012
Gotoh Hideo, Aoyama Hiroaki
Abstract excerpt
Genetic disorders are usually considered to be caused by harmful gene mutations, as well as by chromosomal aberrations, including small insertions, duplications and/or deletions. However, as infertile individuals often arise among the offspring of crosses between two fertile mouse strains, we postulate that a certain combination of 'normal' genes with neither gene mutations nor chromosomal aberrations can cause...
Topics
- Animals
- Crosses, Genetic
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Multifactorial Inheritance
- Mutation
- Phenotype
- Sperm Head
- Spermatogenesis
- Spermatozoa
- Testis