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Article

Podocyte Mitosis – A Catastrophe

1 Dec 2012

Abstract excerpt

Podocyte loss plays a key role in the progression of glomerular disorders towards glomerulosclerosis and chronic kidney disease. Podocytes form unique cytoplasmic extensions, foot processes, which attach to the outer surface of the glomerular basement membrane and interdigitate with neighboring podocytes to form the slit diaphragm. Maintaining these sophisticated structural elements requires an intricate actin...

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PMID: 23176147
DOI: 10.2174/1566524011307010013

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