Article
Signal transduction and osmoregulation in Escherichia coli: a novel mutant of the positive regulator, OmpR, that functions in a phosphorylation-independent manner.
Journal of biochemistry - 1 Apr 1992
Kanamaru K, Mizuno T
Abstract excerpt
In Escherichia coli, expression of the outer membrane proteins, OmpF and OmpC, is regulated by the regulatory factors, EnvZ and OmpR, at the transcriptional level in response to the medium osmolarity. In this particular osmotic regulation, phosphorylation of OmpR at an aspartate residue (Asp-55) by EnvZ plays an important role. The previously isolated mutant, ompR55Q, with the amino acid replacement of Asp-55 to...
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