Article
BRCA1 germ-line mutations and tumor characteristics in eastern Chinese women with familial breast cancer.
Anatomical record (Hoboken, N.J. : 2007) - 1 Feb 2013
Cao Wenming, Wang Xiaojia, Gao Yun, Yang Hongjian, Li Ji-Cheng
Abstract excerpt
Although several studies detected the BRCA1 germ-line mutations in Chinese women with familial breast cancer, most of them did not employ conventional full gene sequencing, especially in eastern China. In addition, the clinicopathological features of BRCA1-associated breast cancer in Chinese women were not well investigated. In this study, we screened the complete coding regions and exon-intron boundaries of...
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