Article
None of the six SNPs of IL28B could predict treatment responses in genotype 2 chronic HCV infected patients by propensity score matching analysis.
PloS one - 1 Jan 2012
Jeng Wen-Juei, Lin Chun-Yen, Chen Ji-Yih, Huang Chang-Wen, Huang Chien-Hao, Sheen I-Shyan
Abstract excerpt
BACKGROUND & AIMS: A combination of pegylated interferon-alpha and ribavirin (PR) is the standard therapy for patients with chronic hepatitis C. The impact of polymorphism of interleukin-28B (IL28B) on sustained virological response (SVR) to PR has been well documented in patients with CHC genotype-1 (GT1), but it is controversial in genotype-2 (GT2) CHC patients. This study investigated the predictability of six...
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