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Article

STAT3 is involved in esophageal carcinogenesis through regulation of Oct-1

21 Nov 2012

Abstract excerpt

The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis and motility in human cancer cells. We aim to elucidate the function of STAT3 in esophageal carcinogenesis process and molecular mechanisms. We showed that hyperactivated STAT3 in esophageal carcinogenesis tissues correlated with the overexpression of octamer transcription factor-1...

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PMID: 23172665
DOI: 10.1093/carcin/bgs361

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