Article
Association of XPD and XRCC1 genetic polymorphisms with hepatocellular carcinoma risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Guo Lian-Yi, Jin Xu-Peng, Niu Wei, Li Xiao-Fei, Liu Bao-Hai, Wang Yu-Lin
Abstract excerpt
AIM: XRCC1 and XPD are two major repair genes involved in nucleotide excision repair (NER), which is reported to be associated with risk of several cancers. We explored the association of XRCC1 and XPD polymorphisms with the risk of HCC. METHODS: A total of 410 cases with HCC and 410 health controls were collected. XRCC1 Arg194Trp, XRCC1 Arg399Gln, XPD Lys751Gln and XPD Asp312Asn genotyping was performed by...
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