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Article

The contributions of wobbling and superwobbling to the reading of the genetic code.

PLoS genetics - 1 Jan 2012

Alkatib Sibah, Scharff Lars B, Rogalski Marcelo, Fleischmann Tobias T, Matthes Annemarie, Seeger Stefanie, Schöttler Mark A, Ruf Stephanie, Bock Ralph

Abstract excerpt

Reduced bacterial genomes and most genomes of cell organelles (chloroplasts and mitochondria) do not encode the full set of 32 tRNA species required to read all triplets of the genetic code according to the conventional wobble rules. Superwobbling, in which a single tRNA species that contains a uridine in the wobble position of the anticodon reads an entire four-fold degenerate codon box, has been suggested as a...

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Identifiers

PMID: 23166520
DOI: 10.1371/journal.pgen.1003076
PMCID: PMC3499367

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Source receipt: pubmed, retrieved 7 Sept 2026.

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