Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription factors link mouse WAP-T mammary tumors with human breast cancer.

International journal of cancer - 15 Mar 2013

Otto Benjamin, Streichert Thomas, Wegwitz Florian, Gevensleben Heidrun, Klätschke Kristin, Wagener Christoph, Deppert Wolfgang, Tolstonog Genrich V

Abstract excerpt

Mouse models are important tools to decipher the molecular mechanisms of mammary carcinogenesis and to mimic the respective human disease. Despite sharing common phenotypic and genetic features, the proper translation of murine models to human breast cancer remains a challenging task. In a previous study we showed that in the SV40 transgenic WAP-T mice an active Met-pathway and epithelial-mesenchymal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Gene Expression Profiling

Share to Mammary Neoplasms, Experimental

Share to Mice, Inbred BALB C

Share to Mice, Transgenic

Share to Transcription Factors

Source

Identifiers

PMID: 23161608
DOI: 10.1002/ijc.27941

Genes

ELF5
HOXA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription factors link mouse WAP-T mammary tumors with human breast cancer.PMID 23161608Read ↗

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterpartsSemantic proximity Read ↗

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumorsSemantic proximity Read ↗

Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancersSemantic proximity Read ↗

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer.Semantic proximity Read ↗

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas.Semantic proximity Read ↗

A susceptibility gene signature for ERBB2-driven mammary tumour development and metastasis in collaborative cross mice.Semantic proximity Read ↗

From Mice to HumansSemantic proximity Read ↗

Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneitySemantic proximity Read ↗

Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cellsSemantic proximity Read ↗

Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivoSemantic proximity Read ↗

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkersSemantic proximity Read ↗

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.