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Article

Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2009

Sharma Gayatri, Mirza Sameer, Yang Yi-Hsin, Parshad Rajinder, Hazrah Priya, Datta Gupta Siddartha, Ralhan Ranju

Abstract excerpt

BACKGROUND: Methylation-mediated suppression of detoxification, DNA repair and tumor suppressor genes has been implicated in cancer development. This study was designed to investigate the impact of concurrent methylation of multiple genes in breast tumors on disease prognosis. METHODS: Methylation specific PCR was carried out to analyze the methylation status of seven genes in archived breast tissues and...

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Source

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Identifiers

PMID: 19940364
DOI: 10.3233/CLO-2009-0507
PMCID: PMC4619044

Genes

BRCA1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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