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Article

Dental abnormalities in a mouse model for craniometaphyseal dysplasia.

Journal of dental research - 1 Feb 2013

Dutra E H, Chen I-P, Reichenberger E J

Abstract excerpt

Mice carrying a knock-in mutation (Phe377del) in the Ank gene replicate many skeletal characteristics of human craniometaphyseal dysplasia, including hyperostotic mandibles. Ank (KI/KI) mice have normal morphology of erupted molars and incisors but excessive cementum deposition with increased numbers of Ibsp- and Dmp1-positive cells on root surfaces. The cervical loops of adult Ank...

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Identifiers

PMID: 23160629
DOI: 10.1177/0022034512468157
PMCID: PMC3545689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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