Dental anomalies in a child with craniometaphysial dysplasia.

Abstract excerpt

Craniometaphysial dysplasia (CMD) is a rare disorder that mainly affects craniofacial bones. It is caused by mutations within a region of human homolog (Ankh) of the mouse progressive ankylosis (Ank) gene. ANK, together with other factors, regulates intracellular and extracellular levels of pyrophosphate/inorganic phosphate critical for maintaining mineral homeostasis. The systemic manifestations noted in CMD...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Craniofacial Abnormalities
• Share to Diphosphates
• Share to Genes, Dominant