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Translating Genomics to the Clinic: Implications of Cancer Heterogeneity

14 Nov 2012

Abstract excerpt

BACKGROUND: Sequencing of cancer genomes has become a pivotal method for uncovering and understanding the deregulated cellular processes driving tumor initiation and progression. Whole-genome sequencing is evolving toward becoming less costly and more feasible on a large scale; consequently, thousands of tumors are being analyzed with these technologies. Interpreting these data in the context of tumor complexity...

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Identifiers

PMID: 23151419
DOI: 10.1373/clinchem.2012.184580

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