Article
Novel checkpoint pathway organization promotes genome stability in stationary-phase yeast cells.
Molecular and cellular biology - 1 Jan 2013
Alver Bonnie, Kelly Maire K, Kirkpatrick David T
Abstract excerpt
Most DNA alterations occur during DNA replication in the S phase of the cell cycle. However, the majority of eukaryotic cells exist in a nondividing, quiescent state. Little is known about the factors involved in preventing DNA instability within this stationary-phase cell population. Previously, we utilized a unique assay system to identify mutations that increased minisatellite alterations specifically in...
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