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Article

MicroRNA-149 inhibits proliferation and cell cycle progression through the targeting of ZBTB2 in human gastric cancer.

PloS one - 1 Jan 2012

Wang Ying, Zheng Xiushan, Zhang Zhiyong, Zhou Jinfeng, Zhao Guohong, Yang Jianjun, Xia Limin, Wang Rui, Cai Xiqiang, Hu Hao, Zhu Cailin, Nie Yongzhan, Wu Kaichun, Zhang Dexin, Fan Daiming

Abstract excerpt

An increasing body of evidence indicates that miR-149 can both suppress and promote tumor growth depending on the tumor type. However, the role of miR-149 in the progression of gastric cancer (GC) remains unknown. Here we report that miR-149 is a tumor suppressor in human gastric cancer. miR-149 expression is decreased in GC cell lines and clinical specimens in comparison to normal gastric epithelial cell and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23144691
DOI: 10.1371/journal.pone.0041693
PMCID: PMC3483266

Genes

ZBTB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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