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Article

MCM8 is required for a pathway of meiotic double-strand break repair independent of DMC1 in Arabidopsis thaliana.

PLoS genetics - 1 Jan 2013

Crismani Wayne, Portemer Virginie, Froger Nicole, Chelysheva Liudmila, Horlow Christine, Vrielynck Nathalie, Mercier Raphaël

Abstract excerpt

Mini-chromosome maintenance (MCM) 2-9 proteins are related helicases. The first six, MCM2-7, are essential for DNA replication in all eukaryotes. In contrast, MCM8 is not always conserved in eukaryotes but is present in Arabidopsis thaliana. MCM8 is required for 95% of meiotic crossovers (COs) in Drosophila and is essential for meiosis completion in mouse, prompting us to study this gene in Arabidopsis meiosis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23300481
DOI: 10.1371/journal.pgen.1003165
PMCID: PMC3536722

Genes

DMC1
MCM8
RAD51
MCM2

Provenance

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Related research

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Research trail→

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MCM8 is required for a pathway of meiotic double-strand break repair independent of DMC1 in Arabidopsis thaliana.PMID 23300481Read ↗

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The Arabidopsis thaliana MND1 homologue plays a key role in meiotic homologous pairing, synapsis and recombination.Semantic proximity Read ↗

Random chromosome segregation without meiotic arrest in both male and female meiocytes of a dmc1 mutant of Arabidopsis.Semantic proximity Read ↗

The Fanconi anemia ortholog FANCM ensures ordered homologous recombination in both somatic and meiotic cells in Arabidopsis.Semantic proximity Read ↗

Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis.Semantic proximity Read ↗

RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis.Semantic proximity Read ↗

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Atmnd1-delta1 is sensitive to gamma-irradiation and defective in meiotic DNA repair.Semantic proximity Read ↗

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