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Article

Field cancerization in mammary carcinogenesis - Implications for prevention and treatment of breast cancer.

Experimental and molecular pathology - 1 Dec 2012

Rivenbark Ashley G, Coleman William B

Abstract excerpt

The natural history of breast cancer unfolds with the development of ductal carcinoma in situ (DCIS) in normal breast tissue, and evolution of this pre-invasive neoplasm into invasive cancer. The mechanisms that drive these processes are poorly understood, but evidence from the literature suggests that mammary carcinogenesis may occur through the process of field cancerization. Clinical observations are...

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Share to Carcinoma, Ductal, Breast
Share to Carcinoma, Intraductal, Noninfiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Combined Modality Therapy

Share to Epigenesis, Genetic

Share to Neoplasm Recurrence, Local

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Source

Identifiers

PMID: 23142414
DOI: 10.1016/j.yexmp.2012.10.018

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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