Article
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools.
Developmental biology - 1 Feb 2013
Ioannou Marilia, Serafimidis Ioannis, Arnes Luis, Sussel Lori, Singh Surendra, Vasiliou Vasilis, Gavalas Anthony
Abstract excerpt
Aldehyde dehydrogenase (ALDH) genes are increasingly associated with stem/progenitor cell status but their role in the maintenance of pluripotency remains uncertain. In a screen conducted for downstream Ngn3 target genes using ES derived pancreas progenitors we identified Aldh1b1, encoding a mitochondrial enzyme, as one of the genes strongly up regulated in response to Ngn3 expression. We found both by in situ...
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