Article
SCN8A as a novel candidate gene associated with bipolar disorder in the Han Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 12 Dec 2008
Wang Yang, Zhang Jing, Li Xingwang, Ji Jue, Yang Fengping, Wan Chunling, Feng Guoyin, Wan Peng, He Lin, He Guang
Abstract excerpt
BACKGROUND: Bipolar disorder (BPD) is a common, severe and recurrent psychiatric disorder. It has been suggested that BPD patients have a higher risk of suicide than patients with any other psychiatric illnesses. A recent study found that suicide attempt was associated with the SCN8A gene, which has been mapped close to one of the BPD susceptibility loci. Thus, SCN8A is likely to be a candidate gene for BPD....
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