Article
Prediction of altered 3'- UTR miRNA-binding sites from RNA-Seq data: the swine leukocyte antigen complex (SLA) as a model region.
PloS one - 1 Jan 2012
Endale Ahanda Marie-Laure, Fritz Eric R, Estellé Jordi, Hu Zhi-Liang, Madsen Ole, Groenen Martien A M, Beraldi Dario, Kapetanovic Ronan, Hume David A, Rowland Robert R R, Lunney Joan K, Rogel-Gaillard Claire, Reecy James M, Giuffra Elisabetta
Abstract excerpt
THE SLA (swine leukocyte antigen, MHC: SLA) genes are the most important determinants of immune, infectious disease and vaccine response in pigs; several genetic associations with immunity and swine production traits have been reported. However, most of the current knowledge on SLA is limited to gene coding regions. MicroRNAs (miRNAs) are small molecules that post-transcriptionally regulate the expression of a...
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