Article
The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease.
Atherosclerosis - 1 Feb 2013
Joshi Parag H, Xu Hongyan, Lestrange Renee, Flockhart Nancy, Kirkland Ben, Vazquez Gustavo, Qian Zhen, Sharma Abhinav, Marvasty Idean, Bhatt Kunal, Brown Charles, Rinehart Sarah, Miller Joseph, Voros Szilard
Abstract excerpt
Little is known about the contribution of genetics and lipoprotein subclasses to the development of coronary artery calcification (CAC) in asymptomatic, first-degree relatives of patients with CAD. We evaluated 100 asymptomatic, non-smoking, lipid-lowering therapy-naïve, first-degree relatives of patients with obstructive CAD through testing for 27 biomarkers, 15 single nucleotide polymorphisms in 12 candidate...
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