Article
Maternal Inheritance of Familial Hypercholesterolemia Gene Mutation Predisposes to Coronary Atherosclerosis as Assessed by Calcium Score in Adulthood.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2023
Mourre Florian, Giorgi Roch, Gallo Antonio, Boccara Franck, Bruckert Eric, Carrié Alain, Hankard Regis, Inamo Jocelyn, Laboureau Sandrine, Moulin Philippe, Valéro René, Béliard Sophie
Abstract excerpt
BACKGROUND: Animal studies have demonstrated that fetal exposure to high maternal cholesterol levels during pregnancy predisposes to aortic atheroma in the offspring. In humans, little is known about the consequences of this exposure on the development of atherosclerotic cardiovascular disease later in life. We wanted to assess whether maternal/paternal inheritance of familial hypercholesterolemia (FH) gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.