Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.

doi:10.1111/j.1530-0277.2012.01897.x

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Article

Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.

Alcoholism, clinical and experimental research - 1 Feb 2013

Miranda Robert, Reynolds Elizabeth, Ray Lara, Justus Alicia, Knopik Valerie S, McGeary John, Meyerson Lori A

Abstract excerpt

BACKGROUND: Emerging research suggests that genetic influences on adolescent drinking are moderated by environmental factors. The present study builds on molecular-genetic findings by conducting the first analysis of gene-environment interactions in the association between a functional single nucleotide polymorphism (SNP) of the μ-opioid receptor (OPRM1) gene (A118G) and risk of developing an alcohol use disorder...

Topics

Adolescent
Adolescent Behavior
Alcohol-Related Disorders
Alleles
Case-Control Studies
Disease Susceptibility
Female
Gene-Environment Interaction
Genetic Association Studies
Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Parenting

Peer Group

Polymorphism, Single Nucleotide

Receptors, Opioid, mu

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23136901
DOI: 10.1111/j.1530-0277.2012.01897.x
PMCID: PMC3700411

Genes

OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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