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Article

The MAOA promoter polymorphism, disruptive behavior disorders, and early onset substance use disorder: gene–environment interaction

1 Dec 2007

Abstract excerpt

OBJECTIVES: Conduct, oppositional defiant, and attention deficit hyperactivity disorders, reflecting early antisociality and behavior dysregulation, are predictive of substance use disorders. Liabilities to these disorders share genetic and environmental variance. Parenting characteristics have been shown to influence development of antisociality, moderated by variation at the MAOA gene, which has also been...

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PMID: 18075472
DOI: 10.1097/ypg.0b013e32811f6691

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