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Article

Association of metabolic obesity phenotypes with cognitive decline in the ELSA-Brasil study.

Diabetes, obesity & metabolism - 1 Apr 2026

Lazzaris Coelho Paulo Henrique, Gomes Gonçalves Natalia, Santos Itamar S, Goulart Alessandra C, Barreto Sandhi Maria, Giatti Luana, Caramelli Paulo, Lotufo Paulo Andrade, Bensenor Isabela Martins, Suemoto Claudia Kimie

Abstract excerpt

AIMS: To investigate the association between metabolic obesity phenotypes and cognitive decline and evaluate the potential mediating role of C-reactive protein (CRP). METHODS: Longitudinal cohort study using three waves (2008-2019) of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Data were analysed from December 2024 to May 2025. Baseline sample consisted of 15 105 participants aged 35-74 years....

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PMID: 41555838
DOI: 10.1111/dom.70466
PMCID: PMC12992203

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