Article
Genetic and epigenetic markers in the evaluation of pancreatic masses.
Journal of clinical pathology - 1 Mar 2013
Ginestà Mireia M, Mora Josefina, Mayor Regina, Farré Antoni, Peinado Miquel Angel, Busquets Juli, Serrano Teresa, Capellá Gabriel, Fabregat Joan
Abstract excerpt
BACKGROUND: Methylation markers have shown promise in the early diagnosis of pancreatic carcinoma. The aim of this study was to assess the diagnostic utility of hypermethylation status of candidate genes in combination with KRAS mutation detection in the evaluation of pancreatic masses. EXPERIMENTAL DESIGN: Sixty-one fine needle aspirates of pancreatic masses (43 pancreatic adenocarcinomas and 18 chronic...
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