Article
DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease.
Cancer research - 15 Jan 2006
Matsubayashi Hiroyuki, Canto Marcia, Sato Norihiro, Klein Alison, Abe Tadayoshi, Yamashita Keishi, Yeo Charles J, Kalloo Anthony, Hruban Ralph, Goggins Michael
Abstract excerpt
Molecular markers of pancreatic neoplasia could aid in the evaluation of visible pancreatic lesions and indicate neoplasia invisible to imaging. We evaluated methylation-specific PCR (MSP) assays that detect aberrantly methylated DNA for their use as markers of pancreatic neoplasia. Methylation analysis was done on pancreatic juice collected endoscopically or surgically from 155 individuals with suspected...
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