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Article

The impact of human gene polymorphisms on HCV infection and disease outcome.

Seminars in liver disease - 1 Nov 2011

Schaefer Esperance A K, Chung Raymond T

Abstract excerpt

In recent years, some genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with hepatitis C viral containment, treatment response, and disease progression. IL28B is a gene on chromosome 19, coding for interferon-λ3, and two polymorphisms upstream of this the gene have been strongly associated with clinical outcomes after treatment for the hepatitis C virus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22189977
DOI: 10.1055/s-0031-1297926

Genes

ITPA
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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