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Article

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.

PLoS genetics - 1 Jan 2012

Amambua-Ngwa Alfred, Tetteh Kevin K A, Manske Magnus, Gomez-Escobar Natalia, Stewart Lindsay B, Deerhake M Elizabeth, Cheeseman Ian H, Newbold Christopher I, Holder Anthony A, Knuepfer Ellen, Janha Omar, Jallow Muminatou, Campino Susana, Macinnis Bronwyn, Kwiatkowski Dominic P, Conway David J

Abstract excerpt

Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading to identifiable signatures of balancing selection. To comprehensively survey for genes under such selection in the human malaria parasite Plasmodium falciparum, we generated paired-end short-read sequences of p...

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PMID: 23133397
DOI: 10.1371/journal.pgen.1002992
PMCID: PMC3486833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23133397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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