Article
ngs (notochord granular surface) gene encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish.
The Journal of biological chemistry - 25 Jan 2013
Tong Xiangjun, Xia Zhidan, Zu Yao, Telfer Helena, Hu Jing, Yu Jingyi, Liu Huan, Zhang Quan, Sodmergen, Lin Shuo, Zhang Bo
Abstract excerpt
The notochord is an important organ involved in embryonic patterning and locomotion. In zebrafish, the mature notochord consists of a single stack of fully differentiated, large vacuolated cells called chordocytes, surrounded by a single layer of less differentiated notochordal epithelial cells called chordoblasts. Through genetic analysis of zebrafish lines carrying pseudo-typed retroviral insertions, a mutant...
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