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Article

Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population.

Rheumatology international - 1 May 2013

Yang Hongju, Wei Chuanyu, Li Qin, Shou Tao, Yang Yan, Xiao Chunjie, Yu Min, Li Ming, Yang Zhili, Zhang Jieying, Zheng Bingrong

Abstract excerpt

Toll-like receptor4 (TLR4) plays an important role in the induction and regulation of the innate or adaptive immune responses. Thus, the genetic variation in TLR4 gene may influence the development of autoimmune diseases such as rheumatoid arthritis (RA). Several studies have investigated the roles of genetic polymorphisms of TLR4 gene in RA, but most of these studies were restricted to two cosegregating...

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PMID: 23129427
DOI: 10.1007/s00296-012-2536-8

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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