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Article

Lack of association of TLR4 gene Asp299Gly and Thr399Ile polymorphisms with rheumatoid arthritis in Chinese Han population of Yunnan Province.

Rheumatology international - 1 Jul 2010

Zheng Bingrong, Li Qin, Wei Chuanyu, Qin Jiao, Shou Tao, Zhou Ruoyu, Shao Jingru, Yang Yan, Xiao Chunjie

Abstract excerpt

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovium and subsequent joint destruction. Recently, genetic polymorphisms within the toll-like receptor 4 (TLR4) genes have been reported to be associated with RA. To analyze the association between the genetic polymorphisms within TLR4 gene and the susceptibility to RA in Chinese people, two functional variants,...

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Source

Identifiers

PMID: 20306049
DOI: 10.1007/s00296-010-1400-y

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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