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Global analysis of mRNA stability in Mycobacterium tuberculosis

2 Nov 2012

Abstract excerpt

Mycobacterium tuberculosis (MTB) is a highly successful pathogen that infects over a billion people. As with most organisms, MTB adapts to stress by modifying its transcriptional profile. Remodeling of the transcriptome requires both altering the transcription rate and clearing away the existing mRNA through degradation, a process that can be directly regulated in response to stress. To understand better how MTB...

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PMID: 23125364
DOI: 10.1093/nar/gks1019

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