Article
A PCR-RFLP method for typing human papillomavirus type 16 variants.
Journal of virological methods - 1 Feb 2013
Lugo-Trampe Ángel, Trujillo-Murillo Karina del C, Rodriguez-Sanchez Iram P, Barboza-Cerda Maria del C, Lugo-Trampe José de J, Hernández-Ramirez Laura C, Canseco-Avila Luis M, Espinoza-Ruiz Marisol, Domínguez-Arrevillaga Sergio, Delgado-Enciso Iván
Abstract excerpt
Infection with some types of human papillomavirus (HPV) is required for cervical cancer development, being HPV type 16 (HPV 16) the most common type in premalignant and malignant cervical lesions. DNA sequencing has revealed the existence of intratypic variants of HPV 16 whose genotyping is clinically useful for distinguishing between persistent and recurrent infections. From the epidemiological perspective, the...
Topics
- DNA, Viral
- Female
- Genotype
- Human papillomavirus 16
- Humans
- Molecular Epidemiology
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
