Article
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines.
The Journal of experimental medicine - 15 Feb 2010
Kisand Kai, Bøe Wolff Anette S, Podkrajsek Katarina Trebusak, Tserel Liina, Link Maire, Kisand Kalle V, Ersvaer Elisabeth, Perheentupa Jaakko, Erichsen Martina Moter, Bratanic Nina, Meloni Antonella, Cetani Filomena, Perniola Roberto, Ergun-Longmire Berrin, Maclaren Noel, Krohn Kai J E, Pura Mikulás, Schalke Berthold, Ströbel Philipp, Leite Maria Isabel, Battelino Tadej, Husebye Eystein S, Peterson Pärt, Willcox Nick, Meager Anthony
Abstract excerpt
Chronic mucocutaneous candidiasis (CMC) is frequently associated with T cell immunodeficiencies. Specifically, the proinflammatory IL-17A-producing Th17 subset is implicated in protection against fungi at epithelial surfaces. In autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APEC...
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