Article
Population genetic correlates of declining transmission in a human pathogen.
Molecular ecology - 1 Jan 2013
Nkhoma Standwell C, Nair Shalini, Al-Saai Salma, Ashley Elizabeth, McGready Rose, Phyo Aung P, Nosten François, Anderson Tim J C
Abstract excerpt
Pathogen control programs provide a valuable, but rarely exploited, opportunity to directly examine the relationship between population decline and population genetics. We investigated the impact of an ~12-fold decline in transmission on the population genetics of Plasmodium falciparum infections (n = 1731) sampled from four clinics on the Thai-Burma border over 10 years and genotyped using 96 genome-wide SNPs....
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