Article
The paradoxical population genetics of Plasmodium falciparum.
Trends in parasitology - 1 Jun 2002
Hartl Daniel L, Volkman Sarah K, Nielsen Kaare M, Barry Alyssa E, Day Karen P, Wirth Dyann F, Winzeler Elizabeth A
Abstract excerpt
Among the leading causes of death in African children is cerebral malaria caused by the parasitic protozoan Plasmodium falciparum. Endemic forms of this disease are thought to have originated in central Africa 5000-10000 years ago, coincident with the innovation of slash-and-burn agriculture and the diversification of the Anopheles gambiae complex of mosquito vectors. Population genetic studies of P. falciparum...
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