Molecular surveillance over 14 years confirms reduction of Plasmodium vivax and falciparum transmission after implementation of Artemisinin-based combination therapy in Papua, Indonesia.

doi:10.1371/journal.pntd.0008295

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Article

Molecular surveillance over 14 years confirms reduction of Plasmodium vivax and falciparum transmission after implementation of Artemisinin-based combination therapy in Papua, Indonesia.

PLoS neglected tropical diseases - 1 May 2020

Pava Zuleima, Puspitasari Agatha M, Rumaseb Angela, Handayuni Irene, Trianty Leily, Utami Retno A S, Tirta Yusrifar K, Burdam Faustina, Kenangalem Enny, Wirjanata Grennady, Kho Steven, Trimarsanto Hidayat, Anstey Nicholas M, Poespoprodjo Jeanne Rini, Noviyanti Rintis, Price Ric N, Marfurt Jutta, Auburn Sarah

Abstract excerpt

Genetic epidemiology can provide important insights into parasite transmission that can inform public health interventions. The current study compared long-term changes in the genetic diversity and structure of co-endemic Plasmodium falciparum and P. vivax populations. The study was conducted in Papua Indonesia, where high-grade chloroquine resistance in P. falciparum and P. vivax led to a universal policy of...

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PMID: 32379762
DOI: 10.1371/journal.pntd.0008295
PMCID: PMC7237043

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