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Article

To tell or not to tell - what to do about p.C282Y heterozygotes identified by HFE screening.

Clinical genetics - 1 Sept 2013

Delatycki M B, Wolthuizen M, Aitken M A, Hickerton C, Metcalfe S A, Allen K J

Abstract excerpt

Hereditary hemochromatosis (HH) is a common preventable disorder of iron overload that can result in liver cirrhosis and reduced lifespan. Most HH is due to homozygosity for the HFE p.C282Y substitution. We conducted a study of screening for p.C282Y in high schools where p.C282Y heterozygotes (CY) individuals were informed of their genotype by letter. We studied whether these individuals understood the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23121079
DOI: 10.1111/cge.12053

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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