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Article

Predicting C282Y homozygote genotype for hemochromatosis using serum ferritin and transferrin saturation values from 44,809 participants of the HEIRS study.

Canadian journal of gastroenterology & hepatology - 1 Oct 2014

Lim Andrew, Speechley Mark, Adams Paul C

Abstract excerpt

INTRODUCTION: The simultaneous interpretation of serum ferritin level and transferrin saturation has been used as a clinical guide to diagnose genetic hemochromatosis. The Hemochromatosis and Iron Overload Screening (HEIRS) Study screened 101,168 North American participants for serum ferritin level and transferrin saturation, and C282Y genotyping for the HFE gene. METHODS: Logistic regression involving a...

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Identifiers

PMID: 25314357
DOI: 10.1155/2014/698352
PMCID: PMC4205907

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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