Article
MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample.
BMC medical genetics - 2 Nov 2012
Zhao Jinying, Forsberg Christopher W, Goldberg Jack, Smith Nicholas L, Vaccarino Viola
Abstract excerpt
BACKGROUND: Atherosclerosis is a complex process involving both genetic and epigenetic factors. The monoamine oxidase A (MAOA) gene regulates the metabolism of key neurotransmitters and has been associated with cardiovascular risk factors. This study investigates whether MAOA promoter methylation is associated with atherosclerosis, and whether this association is confounded by familial factors in a monozygotic...
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