Article
Heritability of arterial stiffness and carotid intima-media thickness: an Italian twin study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 May 2014
Medda E, Fagnani C, Schillaci G, Tarnoki A D, Tarnoki D L, Baracchini C, Meneghetti G, Fanelli F, Alaeddin A, Pucci G, Alviti S, Cotichini R, Brescianini S, Boatta E, Lucatelli P, Nisticò L, Penna L, Salemi M, Toccaceli V, Zini C, Garami Z, Stazi M A
Abstract excerpt
BACKGROUND AND AIMS: Carotid intima-media thickness (IMT) and arterial stiffness parameters, including aortic augmentation index (AIx) and pulse wave velocity (PWV), are independent predictors of stroke and cardiovascular disease. Genetic effects on these traits were never explored in a Mediterranean country. The present study aims to quantify the contribution of genes, environment and age to carotid IMT and...
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