Article
Domains involved in multimer assembly of von willebrand factor (vWF): multimerization is independent of dimerization.
The EMBO journal - 1 Mar 1990
Voorberg J, Fontijn R, van Mourik J A, Pannekoek H
Abstract excerpt
The precursor protein of von Willebrand factor (pro-vWF) consist of four repeated domains, denoted D1-D2-D'-D3-A1-A2-A3-D4-B1-B2-B3-C1-C2. The domains D1 and D2 constitute the amino-terminal pro-polypeptide and the remaining domains mature vWF, generated upon proteolytic processing. We have shown...
Topics
- Animals
- Base Sequence
- Cell Line
- Chromosome Deletion
- Gene Expression
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Plasmids
- Protein Processing, Post-Translational
- Restriction Mapping
- Sequence Homology, Nucleic Acid
- Transfection
- von Willebrand Factor