Article
Global phylogeny of Shigella sonnei strains from limited single nucleotide polymorphisms (SNPs) and development of a rapid and cost-effective SNP-typing scheme for strain identification by high-resolution melting analysis.
Journal of clinical microbiology - 1 Jan 2013
Sangal Vartul, Holt Kathryn E, Yuan Jianfeng, Brown Derek J, Filliol-Toutain Ingrid, Weill François-Xavier, Kim Dong-Wook, da Silveira Wanderley Dias, Pickard Derek, Thomson Nicholas R, Parkhill Julian, Yu Jun
Abstract excerpt
The current Shigella sonnei pandemic involves geographically associated, multidrug-resistant clones. This study has demonstrated that S. sonnei phylogeny can be accurately defined with limited single nucleotide polymorphisms (SNPs). By typing 6 informative SNPs using a high-resolution melting (HR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.