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Molecular epidemiology of a multidrug-resistant Shigella sonnei outbreak in Tunisia (2022-2023) using whole-genome sequencing.

Microbial genomics - 1 Mar 2025

Smaoui Fahmi, Ksibi Boutheina, Mezghani Senda, Guermazi Eya, Charfi Fatma, Ktari Sonia, Ben Ayed Nourelhouda, Kammoun Thouraya, Karray Héla, Hammami Adnene

Abstract excerpt

Purpose. The prevalence of multidrug-resistant (MDR) Shigella sonnei is increasing globally, raising concerns for public health. In 2022, an outbreak of MDR S. sonnei was observed in Tunisia. We aimed to evaluate the genetic profile of S. sonnei isolates during the outbreak, including their clonal relationship, antimicrobial determinants and connection to international strains.Methods. In this study, we sequenced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40048496
DOI: 10.1099/mgen.0.001362
PMCID: PMC11936343

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