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Article

Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis

31 Oct 2012

Abstract excerpt

BACKGROUND: Porphyromonas gingivalis is a Gram-negative anaerobic bacterium associated with periodontal disease onset and progression. Genetic tools for the manipulation of bacterial genomes allow for in-depth mechanistic studies of metabolism, physiology, interspecies and host-pathogen interactions. Analysis of the essential genes, protein-coding sequences necessary for survival of P. gingivalis by transposon...

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PMID: 23114059
DOI: 10.1186/1471-2164-13-578

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